Review

Genetic recombination in bacteriophage lambda

Christopher R. T. Hillyar

Durham University, South Road, Durham DH1 3LE, UK

Received:

30 Sept 2011

Accepted:

1 Jan 2012

Published:

7 Mar 2012

Volume:

5

Issue:

1

Keywords:

recombination, lambda, orf, Exo, beta, Rap

Abstract:

Bacteriophage λ (lambda) infects Escherichia coli and induces a dramatically increased rate and altered profile of genetic recombination as part of the cycle of infection. The genetic recombination processes augment the host-encoded recombination proteins with phage-encoded recombination proteins, promoting particular recombination pathways. This review characterizes the protein machinery involved in the most important processes underlying λ-mediated genetic recombination.

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